By car: (Melways map ref. 70 G10)
The trip will take about 30 minutes from the city centre along Citylink (tolls apply) and the Monash Freeway. If using Eastlink (tolls) from the north or south, use the Monash Freeway interchange and travel west.
If travelling from Melbourne airport add 15 minutes via Citylink (tolls).

By train: to get to Clayton campus by public transport, take any of the Dandenong, Pakenham or Cranbourne line trains to Huntingdale station then catch a bus to the campus. Buses leave the station for Clayton campus every 15-20 minutes.

By bus:

Buses stopping at the Clayton bus loop:

• 630, between Elwood and Monash University
• 631, between Waverly Gardens SC and Southland shopping centre
• 691, between Bayswater and Waverley Gardens
• 703, between Blackburn and Middle Brighton
• 733, between Box Hill and Oakleigh
• 737, between Croydon and Monash University
• 802/804/862, different routes between Dandenong and Chadstone shopping centre

Other buses include:

• 742, between Eastland and Chadstone which stops at the back of the University on the ring road
• 800, between Dandenong and Chadstone which stops approximately 0.5km from the University on Dandenong Road